{"id":16673,"date":"2026-06-05T16:37:28","date_gmt":"2026-06-05T08:37:28","guid":{"rendered":"https:\/\/www.tigerandtech.com\/?p=16673"},"modified":"2026-06-05T16:37:30","modified_gmt":"2026-06-05T08:37:30","slug":"jin_nian_quan_shi_shou_kuan_tuo_le","status":"publish","type":"post","link":"https:\/\/www.tigerandtech.com\/en\/jin_nian_quan_shi_shou_kuan_tuo_le\/","title":{"rendered":"First one in the city this year, and it's done!"},"content":{"rendered":"

June 4A product called \"Vimatrol\u00ae<\/strong>\"<\/strong>(Generic name: anritriptanib) in a class of innovative medicines<\/strong>From the Biomedical Valley of the New District, through prioritized review and approval.catch<\/strong>Approved for marketing by the State Drug Administration<\/strong>, for the treatment of adult and adolescent patients over the age of 12 with solid tumors carrying the NTRK fusion gene.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

This is the first one approved for listing in Nanjing this year.<\/strong>Innovative medicines<\/strong>Vimetal\u00ae is the third new generation TRK inhibitor in the world. As a \"cancer-free\" anti-cancer drug, Vimetal\u00ae will bring new treatment options to more solid tumor patients.<\/p>\n\n\n\n

This \"Jiangbei-made\" innovative drugs, the value of geometry<\/strong><\/p>\n\n\n\n

If I were to introduce this innovative drug in one sentence, it would go something like this:As long as the tumor carries a substance called<\/strong>\"NTRK gene fusion\" is a specific marker, regardless of where it grows in the lungs.<\/strong>In the mammary glands.<\/strong>nevertheless<\/strong>thyroid (gland)<\/strong>Glandular, Vimetal<\/strong>\u00ae can be precisely targeted and \"locked\".<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

To read about this breakthrough, you have to talk about the story behind it.<\/p>\n\n\n\n

In our bodies, there is a family of genes called NTRK, which when fused with other genes, produce an abnormal TRK fusion protein that drives unlimited cell proliferation and eventually leads to tumors.<\/p>\n\n\n\n

It is understood that NTRK gene fusion is widely present in more than 45 cancer types. Although the overall proportion is not high, China has a large population base, with about 15,000 new cases of tumors carrying NTRK fusion genes each year.these patients<\/strong>invariably<\/strong>Poor prognosis, short survival, rapid disease progression and susceptibility to brain metastasis<\/strong>. Even trickier, first-generation TRK inhibitors often develop resistance after use, leaving treatment in limbo.<\/p>\n\n\n\n

Vimetal\u00ae is here to break the ice for this very reason.<\/p>\n\n\n\n

The relevant person in charge of the enterprise introduced this drug has three highlights: first, the efficacy is remarkable, the results of the registered clinical studies show that theTumor shrinkage or stability in patients with super 85% after treatment with<\/strong>Secondly, the drug has strong brain penetrating activity, and in clinical trials, it also achieved an objective remission rate of nearly 90% in patients with brain metastases; thirdly, the innovative cyclic molecular structure of Vimetal\u00ae can effectively avoid the problem of drug-resistant mutations.<\/p>\n\n\n\n

\"This is a broad-spectrum anticancer drug that is not limited to specific tumors.\" Dr. Yanchun Gong, co-founder, chairman, and CEO of Wickell Pharmaceuticals, said thatThe entire project started with<\/strong>Clinical Application<\/strong>Approved to Market Approval in<\/strong>More than five years<\/strong>, all the teams and partners involved in R&D are moving forward at full speed, just to give more solid tumor patients earlier access to better quality treatments.<\/p>\n\n\n\n

It is worth noting that this innovative drugIncluded in the \"Pilot Program to Encourage Pediatric Antitumor Drug Development (Starlight Program)\" by the State Drug Administration.<\/strong>, clinical trial work for NTRK-resistant patients is also advancing rapidly.<\/p>\n\n\n\n


From a new drug to a \"drug valley\".<\/strong><\/p>\n\n\n\n

Of course, Vimetal\u00ae is not alone in its creation.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

If you cast your eyes to the new area of biomedical valley, you will find that under the Dragon King Mountain, the innovative drug reports frequently sound. In this \"valley\", a series of good drugs with memorable names have come out---<\/p>\n\n\n\n

Precedent Pharmaceuticals'\"First must be new.\"<\/strong>series, from injections to sublingual tablets, has snatched precious time for countless stroke patients to save their lives; Reindeer Bio's CAR-T cell therapyFocosol\u00ae<\/strong>The company has benefited hundreds of patients and attracted more than 40 overseas patients to China for treatment; Zhenxiang Pharmaceutical'sCiclosporin\u00ae<\/strong>, giving flu treatment a new domestic option ......<\/p>\n\n\n\n

To date, the Valley has<\/strong>7 new drugs of the first class were approved for marketing. Last year, the city's three new drugs of a class, the Valley \"contributed\" two of them.<\/strong>It is important to know that in the field of biopharmaceuticals, new drug research and development usually has the \"three laws of ten\" - that is, it takes ten years, one billion dollars investment, ten percent success rate, a new drug is called the biopharmaceutical industry, \"the crown jewels\". The value is self-evident. The value is self-evident.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Not only these seven listed class I new drugs, in the Valley, there are many companies are targeting the clinical hard to gnaw the \"hard core\" launch of new drugs, the park will be a solid public technical service platform, complete upstream and downstream industry chain as well as accurate policy support, all the way to escort the growth of the park.<\/p>\n\n\n\n

Today, more \"seeds\" are breaking ground in the park's laboratories.A number of new drugs pipeline ladder clear, full of strength, they may be the next \"city's first\", the next \"global new\".<\/strong><\/p>\n\n\n\n

The story of innovation has just turned a fascinating chapter at the bottom of Longwang Mountain.<\/p>\n\n\n\n

\"\"<\/figure>","protected":false},"excerpt":{"rendered":"

On June 4, an innovative Class I drug called \u201cWeimaitou\u00ae\u201d (generic name: anretinib) was launched from the New District Biomedical Valley. After undergoing priority review and approval, it received national [\u2026]<\/p>","protected":false},"author":2,"featured_media":16675,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[84],"tags":[],"class_list":["post-16673","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chan_ye_lian_xun_xi"],"acf":[],"yoast_head":"\n\u4eca\u5e74\u5168\u5e02\u9996\u6b3e\uff0c\u201c\u59a5\u201d\u4e86\uff01 - \u6c5f\u82cf\u5c0f\u864e\u79d1\u6280\u53d1\u5c55\u6709\u9650\u516c\u53f8<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.tigerandtech.com\/en\/jin_nian_quan_shi_shou_kuan_tuo_le\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u4eca\u5e74\u5168\u5e02\u9996\u6b3e\uff0c\u201c\u59a5\u201d\u4e86\uff01 - 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